: News :
Ad ID: 4421
Added: April 15, 2019
New role for sensory signals in the brain: Findings could help lead to new treatments for Parkinson
Learning how to tie a shoe or shoot a basketball isn’t easy, but the brain somehow integrates sensory signals that are critical to coordinating movements so you can get it right.
Now, Rutgers scientists have discovered that sensory signals in the brain’s cerebral cortex, which plays a key role in controlling movement and other functions, have a different pattern of connections between nerve cells and different effects on behavior than motor signals. The motor area of the cortex sends signals to stimulate muscles.
The research on neural signals, published in the journal Current Biology, could help lead to new treatments for movement disorders such as Parkinson’s disease and Huntington’s disease or psychiatric conditions such as obsessive compulsive disorder.
Scientists at Rutgers University-New Brunswick and Rutgers-Newark investigated a brain region called the striatum in mice. The striatum, which integrates signals from the sensory and motor areas of the cerebral cortex, is severely compromised in diseases such as Parkinson’s and Huntington’s.
“We found that stimulation of sensory cortex signals caused mice to stop their actions during a behavioral task, but motor cortex signals caused them to perform the task more impulsively,” said senior author David J. Margolis, an assistant professor in the Department of Cell Biology and Neuroscience in the School of Arts and Sciences at Rutgers-New Brunswick.
Future research will investigate the patterns of signaling between the cerebral cortex and striatum during different types of learning paradigms in mice to understand nerve cell connection mechanisms. The ultimate goal is to understand how abnormal cortex-striatum signaling is involved in neurological and psychiatric disorders.
The purpose of our website is only to help students to assist, guide and aware them regarding material available. Moreover, it is necessary for you to take the permission if you want to reproduce or commercial purpose.
*All the rights reserved by Developer and Translator.
Help Us Improve This Article
Did you find an inaccuracy? We work hard to provide accurate and scientifically reliable information. If you have found an error of any kind, please let us know.
Add comment. we appropriate your effort.
Share with Us
If you have any scale or any material related to psychology kindly share with us on firstname.lastname@example.org. We help others on behalf of you.